The Somaliland HIV National Strategic Plan and M&E Framework2021 to 2023 has been developed to support a coordinated, evidence-based and contextualised national response to the epidemic. This Somaliland HIV NSP serves to: (i) Articulate a strategic framework for the implementation of the multi–sectoral HIV and AIDS response guided by one NSP and one Monitoring and Evaluation (M&E) framework; (ii) Identify and articulate priorities and results for the multi –sectoral HIV and AIDS response; (iii) Enable decentralized planning and implementation framework where communities identify their strategic priorities, and design and implement appropriate evidence-based and results-focused interventions that contribute to results (targets);and (iv) Provide a resource mobilisation tool for the HIV and AIDS response. This NSP was developed through a highly consultative, participatory and evidence-driven process over a period ofseveralmonths under leadership of the Somaliland National AIDS Commission (SOLNAC) with multiple stakeholders’ consultation activities. The NSP articulates a strategic direction that builds on the understanding of the epidemiology and the existing structural, legal and other barriers required, to acceleratean end to the HIV epidemics in Somaliland, a complex operating environment.